A Glimpse into the Future of Nuclear Medicine

Our FrameWORX series this year has been a fascinating journey through the pillars of our strategic life sciences plan for Indiana. Our final event of the year – held earlier this month at the Indiana Biosciences Research Institute – can feel like a big gulp of science. But no area captures Indiana’s life sciences growth like nuclear medicine and radiopharmaceuticals.

Indiana leads the nation in conventional pharmaceutical exports, and at least 14 life sciences companies today are developing and manufacturing radiopharmaceuticals – propped by our state’s central location and logistics expertise. Decades of life sciences leadership are complemented by the logistics required to produce treatments and diagnostics that leave little room for shelf life. Radioactive materials degrade quickly, and each dose must reach the intended patient within 3 to 5 days from production. Indiana’s FedEx hub, the second largest in the world, is a major advantage – as is the fact Central Indiana is a 12-hour drive from approximately half the U.S.

Indiana is on the leading edge of a booming technology. Nuclear medicine is a $6 billion industry in the U.S. and is expected to triple in the next 7 years. Heartland BioWorks, designated a regional technology and innovation hub by the federal Economic Development Administration, has established BioTrain, an institute designed to prepare talent for entry-level biomanufacturing roles. BioTrain will be located at the 16 Tech Innovation District. And just north of Indianapolis, Purdue has the nation’s largest nuclear medicine pharmacy program in the country.

As demonstrated at our FrameWORX, radiopharmaceuticals are used in nuclear medicine imaging and procedures – particularly for prostate and other cancers. They are administered systemically, but their biomolecular properties cause them to localize in specific tissues. Years ago, doctor might use a sledgehammer approach to treatment – in other words, diagnose and treat a large swath of the body to address diseases that were challenging to pinpoint. Radiopharmaceuticals are more like using an arrow and bull’s eye. Precision leads to less invasiveness and more precise treatments for patients.

Researchers and business leaders from IU School of Medicine, Purdue, life sciences companies, and the patient advocacy world drove a robust discussion about the future of radiopharmaceuticals. Perhaps no one said it better than Geoff Towle, a vice president and senior general manager at Novartis. Geoff joined us from his New Jersey headquarters because his company has built a large radiopharmaceutical manufacturing plant in Indianapolis.

“This feels like reimagining medicine,” he said. “Nuclear medicine is incredibly effective and exquisitely targeted. Patients are waiting for this and that’s what we need to focus on."

Thank you to our December FrameWORX Presenting Sponsor